MSM for Knee Arthritis Disappointing by Self

Use of MSM (methylsulfonylmethane) for knee arthritis barely reached significance and did not reach clinical usefulness by self – maybe better if combined with NSAID’s?

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Posted in arthritis, Drugs, Knee | Leave a comment

Ketamine For Depression Confirmed

Press release by A. Shah from Baylor College confirms that ketamine works well for depression. Press release makes a statling comment: “Prozac and other treatments each improve conditions for only about 30 to 40 percent of the patient population, barely outperforming placebos; meanwhile, a single infusion of ketamine washes away the symptoms of 80 to 90 percent of patients who try it, Shah said”

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Posted in Depression | 6 Comments

Cynical Sayings

I got a recent piece of spam that said:

God must love stupid people. He made SO many.
(My inner self is telling me I don’t need to go to the gym so I think there is a little of that in everyone…)

Anyway I thought I would start making a list of cynical sayings for no reason than I like them – feel free to contribute to the list…

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Posted in Uncategorized | 1 Comment

Menstrual Cramps – “Marked Reduction” Following 3 Month Omega 3

Omega 3 improved menstural cramp pains and need for ibuprofen after 3 months use.

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Skin Nerve Stimulation (TENS) Could Treat and Prevent Post Shingles Neuropathic Pains

Transcutaneous Nerve  Stimulation (TENS = TNS)with one pad paraspinous and one pad front at level of shingles run 30 min daily – 20-40 hertz and 1-5 milliamps ended up with no pain at 6 months one versus 10% postherpetic neuralgia in drug treated or no treatment groups. Bizarrely, addition of anti-viral drugs to TNS prevented the beneficial effects.

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Posted in neuropathic, post herpetic neuralgia | Leave a comment

Glossopharyngeal Neuralgia – Treated by Steroid Injection and Amitriptyline

I got a question on what could be done for Glossopharyngeal neuralgia and came across this article on repeated bilateral intraoral glossopharyngeal nerve injections and amitriptyline as an alternative.

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Posted in Injection, neuropathic, Trigeminal Neuralgia | 1 Comment

Sciatica Back Epidural or Caudal – 40 mg Steroid as Good as 80 mg.

In two separate studies, there seemed to be no advantage to using 80 mg steroid over 40 mg. If one stuck to 40 mg, then one could have a shot every 6 weeks, rather than having to wait 3 months for another shot.

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Posted in Uncategorized | 4 Comments

Mixed Drug Treatment Of Interstitial Cystitis(IC)/Painful Bladder (PB) Syndrome

With an increased drug sensitivity, subjects with IC/PB do not handle medications very well. Drugs specifically designed for their condiition (like Elmiron and intra-bladder DMSO)) do not work well. The beauty of this therapy was low does of multiple medications that seem to make a difference.

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Posted in Interstial Cystitis/Gynecologic | Leave a comment

Interstitial Cystitis/Painful Bladder – What are the Genetic Correlates?

Twin studies have found genetic linkages  of IC/painful bladder syndrome with several diseases – Irritable bowel,  prior physical abuse,  frequent headaches,  multiple drug allergies, and self reported bladder infections.

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Confirmed – Alkalanized lidocaine works for Interstitial Cystitis – and Better Yet With Heparin

In a controlled trial,”a combination of 50,000 units of heparin (Baxter), 200 mg lidocaine hydrochloride (Hospira), and 420 mg sodium bicarbonate in 15 mL of water”  instilled in the bladder, using a “hydrophilic LoFric 10 French catheter was used to minimize urethral trauma” gave significant relief of symptoms over the 12 hours of the trial.

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Dengue Fever Scale

Always a risk in some developing countries  – but never had a clear picture of the features like this. More for my reference…

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Confirmation of Nerve Growth in Tendonopathy – in Shoulder Too

I have previously written:
Does Pain “Grow” at Tendon injury sites? -and Treatment tennis elbow

Now for shoulder tendonopathy, “increases of newly grown nerve fibers and blood vessels ” inside tendons has been found

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Posted in Rheumatic, shoulder, tendonitis | Leave a comment

Lithium Reduces Spinal Cord Damage Pain by 35% in 6 Weeks

Case reports have found lithium carbonate an effective in chronic pain but these results have been ignored because of lack of a reliable study, Now a a double-blind, randomized, placebo-controlled clinical trial was done and showed benefit in Chronic  Spinal cord injuries.

 

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Posted in Back Pain, central & spinal, Drugs, neuropathic, radiculitis | Leave a comment

COMT Pain Genes Wreak Havok – Finally a Good Study

Had a pateint with severe pains out of proportion to what one would expect. He has a couple of pain conditions that ran in family and I felt probably had pain genes that augmented the condition. Insurers treated him with complete disdain because of their ignorance. COMT genes have inconsistently showed hypersensitivity to pain stimuli. In order to get consistent results,  the pain system had to be repeatedly stimulated – and then results were obvious. I guess I can add one stimulation studies to my “one – injection shot MORON studies” [expecting one shot to cure or control a pain condition] list.

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Morton’s Neuroma Surgery – severe foot pain option

Morton’ neuroma causes pain in the 3-4th metatarsal head areas with numbness in the corresponding 3rd and 4th toes. The pain, including burning pains in area can become extreme. Surgical removal works well 51-85% of time.

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Posted in Leg Pains, neuropathic | Leave a comment

Midfoot Pains – Response to Injection

Over 1/2 of patients will get sustained relief of midfoot pain for 3 months with steroid injection

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Posted in arthritis, foot, Leg Pains | Tagged | Leave a comment

Simple Sciatic Leg Pain Relief – Repeated Simple Knee level Peroneal Blocks

Repeated peroneal nerve blocks can remarkably control sciatica leg pains in most cases and avoid the necessity of surgery

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Posted in Back Pain, Leg Pains, neuropathic, radiculitis | 3 Comments

Sciaitica, Bone Cyst in Ilium, and Gluteal Tight Muscles – down right leg – needs help

Chronic sciatica /buttock pain  – I recently received a request for help…

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Posted in Back Pain, Hip Pains, Injection, myofascial pain, neuropathic, piriformis, radiculitis | 1 Comment

Chronic Post Root Canal Pain Happens and What Can Be Done?

Series on Reviews puts post root canal chronic pains >6 months anywhere from 5% to over 7%.  Cases have been treated with Botulinum.

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Severe Ankle Pain – No Cause – Ankle CRPS and Oral Biphosphamates Might Fix and Anterolateral impingement

Recently had a cause of severe ankle pain in a pain prone patient. Complex  Regional Pain Syndrome  (CRPS) – aka. Reflex Sympathetic Dystrophy might be a possibility and it now appears oral risedronate 2.5mg per day, or alendronate at 35mg per week can reverse the damage. Exaggerated response to impingement might intervene.

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Posted in ankle, complex regional pain | 1 Comment

Chronic Back Pain Help – Forgotten B12 Injections and What Else Good For…

Double blind, randomised, placebo – controlled trial of daily 1000U IM/day B12 for 14 days found significant benefit for people with chronic Low Back Pain. Cochrane review thought it was not high quality but sounded good to me; and for a non-drug company sponsored study, there is probably no money to do a better one. This was written in 2000 and no one has probably heard about it. Continue reading

Posted in Back Pain, Deficits, Drugs | 7 Comments

The Forgotten Tests For Diabetic Neuropathy – Ankle Jerks and Vibration Testing Sensitive

Pinprick testing is not as accurate as ankle jerks and vibration testing in Diabetic peripheral neuropathy.

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Endometriosis Involves Nerve Fiber Growth Disease – Not In Head

Womb lining (Endometrium)of those with endometriosis (those with womb lining outside the womb) have six times the nerve fivers in the emdometrial lining. This is got to hurt…

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Epicrania fugax – Like a Trigeminal Neuralgia of the Scalp

Have a case of lancinating severe jabs to right top of head. She had them before but they have recently returned. There was no trigger zone, no tenderness, and occipital, temporal and supraorbital nerve trunks were nontender. Write up on subject describes it like a trigeminal neuralgia of the scalp but with differences.

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Posted in Headaches, neuropathic, Trigeminal Neuralgia | Leave a comment

Chronic Migraines – Botulinum Helps

Repeated OnabotulinumtoxinA shots can reduce chronic migraine headache frequency from 20 headaches/month to 10/month.

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Posted in Botox, Headaches, Injection | Leave a comment