Category Archives: central & spinal

Pramipexole Stops MS in Animal Model – Helps Restless Legs, Fibromyalgia, and May Help Resistant Depression

In the mouse model of Multiple Sclerosis, Pramipexole, a antiparkinson drug, stops the brain neuroinflammation and that form of MS called “Experimental Autoimmune Encephalomyelitis”. This agent is used extensively for restless legs – Got MS and restless legs? – I … Continue reading

Posted in central & spinal, Drugs, Leg Pains, Uncategorized | 1 Comment

Resistent Post Herpetic Neuralgia Treatments – IV Magnesium for Neuropathic Pains

Three IV Magnesium  1mg /k in 100 mls saline  infusions over 1 hour – one every other day or Three 1 mg/kg Ketamine in 100 mls saline infused in over 1 hour ketamine  one EOD resulted in 7/15 magnesium and … Continue reading

Posted in central & spinal, complex regional pain, Drugs, IV therapy, neuropathic, Pain Dystrophy, post herpetic neuralgia, radiculitis | 1 Comment

Fibromyalgia(FM) – Quetiapine XR (Seroquel) Reduces Pain Similar to Others and Reduces Depression – But Drowsiness High

FM could be considered a neurodegenerate disorder with certain degrees of brain loss and cognitive impairment evident. Some years ago I was at a presentation in which the brain damage evident in Fibromyalgia was bemoaned by speaker. Having dealt with … Continue reading

Posted in central & spinal, Fibromyalgia, pain mechanisms | 2 Comments

Obscure Groin Pain Could Be Lumbar Disc Even if Back Not Painful

Five  cases of groin pain that refused deliniation  and had NO back pains. They all turned out to be L4/5 or L5/S1 disc pain found on discogram/discoblock.  They all got relief with anterior intrabody fusion.

Posted in Back Pain, central & spinal, neuropathic | Leave a comment

Human Chorionic Gonadotrophin (HCG) Touted as Only Curative Agent For Pain That Has Centralized

When pain becomes severe, constant, and unremitting –  chances are high the pain has imprinted on the brain and centralized. This is a tragic disease with poor treatment options. In those that persisted with treatment (failures may have dropped out?) … Continue reading

Posted in central & spinal, complex regional pain, Fibromyalgia, Injection, neuropathic, pain mechanisms | 1 Comment

Lithium Reduces Spinal Cord Damage Pain by 35% in 6 Weeks

Case reports have found lithium carbonate an effective in chronic pain but these results have been ignored because of lack of a reliable study, Now a a double-blind, randomized, placebo-controlled clinical trial was done and showed benefit in Chronic  Spinal … Continue reading

Posted in Back Pain, central & spinal, Drugs, neuropathic, radiculitis | Leave a comment

Cranial Electrical Stimulation (CES) Helps Post Spinal Cord Injury(SCI) Pain

Skin surface CES therapy is usually 2 milliamp therapy with anode over motor cortex strip (C3) (on skin) with a cathode lead on forehead. In SCI patients it resulted in significant pain relief (P<0.03 versus sham). They found the effect … Continue reading

Posted in central & spinal, Mechanical aids, Stimulation | Leave a comment

Body’s Painkilling Endorphin Response Absent in 25% of Victims with Chronic Pain

The endorphin system in the brain and its counterpart enkephalin system in the spine help to shut down pain awareness in acute situations. Had a bad headache that suddenly disappeared? That is that system kicking in. This system is called … Continue reading

Posted in central & spinal, pain mechanisms | Leave a comment

Possible Cure for Parkinson and Central Pains – Gamma Knife the Thalamus

Gamma knife (GK) thalamotomy was used in cases of pain with Parkinson disease and other central pains.”A clinical success rate of approximately 80% with negligible complications” was achieved.

Posted in central & spinal | Leave a comment

Post-Stroke Pain – New Hope – Vestibular Stimulation and Maybe for Spinal Pain too

Post- stroke victims with central pain can be left with excruciating pain, often one whole side. If their vestibular system is intact (absence of “marked post-stroke disequilibrium.”), then one cold water ear irrigation can drop pain scale levels by more … Continue reading

Posted in central & spinal | 1 Comment