Remarkable New Treatment – Injecting Over Tenderized Skin Nerves With Plain 5% Dextrose

For year I felt the main expression of chronic pain was through activation of myofascial knots – now it looks like tenderized skin nerves is a front runner. Merely injecting D5W overtop tenderized nerve tracts an average of 6 weekly times can settle down even recalcitrant back pains.

Lyftogt, John.
Prolotherapy for recalcitrant lumbago.
Aust Musculoskeletal Med 13.1 (2008): 18-20.

Cutaneous skin nerves come out the back at every level: (from Wikipedia)

  • If you feel for these nerves – they can be palpated and if tender become targets for injection
  • study took 41 cases recalcitrant lumbago with or without leg pains
  • Injected Dextrose – eventually settled on 5% overtop (not in) tender nerves every 2 cm (1 ml each spot)
  • 3 areas settled on included:
    Superior Cluneal Nerves (Red 1)
    Intermediate Cluneal Nerves – near PSIS and SI joint (Red 2)
    Thoracic Cutaneous nerves (Red 3) – notice – can come out bit of way from spine
  • Injected Dexrose blebs on top of tender (only injected tender) 1 ml every 2 cm or so until entire nerve tract numb – helps to pinch up skin and inject superficially
  • Check after to see if numb and inject areas that missed
  • first time relief is a few days or so, then longer
  • People needed average 6.3 weekly treatments though  ranged from 2-16
  • Results:

  • “Ninety percent of patients improved more than 50%, and 10% less than 50%. Twenty-nine percent of patients reported no pain at the last consultation.”

Comment – Adding 3% glycerin (by volume) to D5W or using mannitol apparently makes it work better.  I have had cases that I have worked on for some time now walk out better (and perplexed that they had to wait so long for me to do it). It works as well on leg and neck pains. I will have to talk more on this but just got back from a workshop 6 weeks ago..   John Lyftogt is big on using 1000 u/ml vitamin D cream to settle the voltage-gated calcium channels that he believes are part of the problem… Recently I had a case of knee pains that did not settle with steroid injection.  She had sharp intermittent pains not weight-bearingly increased. She was very tender over the infrapaetllar nerves inferior to joint, and 3% glycerin in D5W injections overtop these areas gave immediate relief… I am now getting recalcitrant cases better!

This entry was posted in Back Pain, Injection, Leg Pains, Neck. Bookmark the permalink.

4 Responses to Remarkable New Treatment – Injecting Over Tenderized Skin Nerves With Plain 5% Dextrose

  1. eric says:

    How/where can I get a 5% Dextrose solution? This issue sounds like exactly what I need on a condition that hasn’t responded to steroids, salves, anything, and which doctors have given up on. I can’t wait to try the overtop method, but need the Dextrose solution. .
    thank you!
    This is standard IV infusion material called D5W.

    • Louise B. Andrew MD says:

      Eric, Lyftogt frequently uses Mannitol for this perineural or superficial nerve injection therapy. One of his students from Vancouver BC has developed a fast absorbing Mannitol cream, called QR creme (for Quick Relief) that is available on Amazon and in Canadian drug stores.
      Assuming you are not a physician, you should definitely NOT be injecting yourself. But you might get relief from this topical preparation. Good luck!

      Dr. Helene Bertrand of UBC is a friend and when she prolotherapied my shoulder she used dextrose. She has developed a “QR cream” of 25-30% mannitol in a vanishing cream for use in neuropathic pain though is field testing a formulation with mannitol and menthol for diabetic neuropathy:

  2. Ken Edwards says:

    I live in New Hampshire. I am interested in where I can receive the new treatment of injecting over tenderized skin nerves with plain 5% dextrose. I can travel to Maine, Vermont or Massachusetts if necessary. I would appreciate it very much if you can assist me in this endeavor.

    Ken Edwards
    The American Association of Orthopaedic Medicine (AAOM) would probably know – they have a search engine but not coming up with much – maybe call them?

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