Author Archives: admin

Helps to Diagnose Hypermobility / Ehlers–Danlos syndrome

German journal article has good templates for diagnosing Ehlers–Danlos syndrome and I thought the world should share this…

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6 Month High Dose Methotrexate For Early OA Hands

6 months of 20 mg Methotrexate can improve significant early hand OA by 25%.

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Pregabalin and Gabapentin Can Worsen COPD Flares

Patients on gabapeninoids (gabapentin and pregabalin) for pain or epilepsy that have COPD are up to 1.5 times more likely to have a severe exacerbation. This scares me.

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Clavulin Might have helped Chronic Low Back pain by Affecting Glutamate in the Brain

Amoxicillin-clavulanic acid 100 day treatment was shown to have significant effect on chronic low back pain yet straight penicillin did not. Recent works on clavulanic drugs has demonstrated it can lower brain glutamate levels (pain transmitter) and help with withdrawal … Continue reading

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What Does One Use For Worst Topical Pains – Lidocaine2.5% /Prilocaine 2.5%

I remember lidocaine/prilocaine mix as Emla – used to put on sites for those terrified of needle pokes. It didn’t have “poison prevention packaging” and was removed from market though generics are available or compounding pharmacy can make up. Was … Continue reading

Posted in Drugs, neuropathic, skin, Topical Pain Treatments, Uncategorized | Leave a comment

Irritable Bowel (IBS) Treatment -Amitriptyline Maybe

Drug treatment for IBS has been fraught with problems of efficacy and wrought with issues of excessive expense. Amitriptyline, an old serotonin simulator, is cheap, helps one sleep, and recently found sort of efficacious.

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Gene Therapy Coming of Age – Sickle Cell With a Catch

Eradicating your bone marrow stem cells, and replacing with gene edited cells can cure the disease but leaves one sterile.  Preemptive egg and tissue freezing and sperm banking  saves the day but can cost up to $20,000 US dollars ( … Continue reading

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Anxiety – Mouthwatering Relief with Stellate Blocks

Anxiety /GAD levels reduced to HALF with stellate ganglion blocks- better results with bilateral,

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Stellate Block for Long COVID 19

In 41 case, right sided stellate block gave rapid relief of brain fog and  fatigue often within 15 minutes of injection. Magical.

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Cannabinoids Not So Great For Pain

In my younger days, there was a group of pain experts that used opioids as their linchpin. Then studies came our showing only 1/2 can tolerate them and only 1/4 will stay on them. Opioid abuse reared its head. Pain … Continue reading

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Multiple Sclerosis / MS helped by Probiotics

Saccharomyces boulardii supplement for four months reduced pain by 31% versus 12.5% by placebo. Fatigue reduced by 19% versus 8% by placebo. Asghari, K.M., Dolatkhah, N., Ayromlou, H. et al. The effect of probiotic supplementation on the clinical and para-clinical … Continue reading

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Acute Nerve Injury – Fasting and No NSAID’s

Fasting promotes growth of Clostridium sporogenes which elevates levels of indole-3-propionic acid (IPA).  In mouse model, improves “promotes neutrophil infiltration into the dorsal root ganglia (DRG), which enhances the regeneration of sciatic nerve fibers”. Nerve growth is contingent on a … Continue reading

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New Hope For PTSD – Bilateral Stellate Blocks/Botulinum/Radiofrequency +/- Ketamine

For years now, stellate ganglion blocks have been found to help anxiety and PTSD. Some are spectacular and some not. Most have been right sided stellate blocks only. Now a case with BILATERAL stellate blocks has been done with initial … Continue reading

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Pain Mechanisms and Patients in Acute Pain are Screwed

It has been widely shown that neuropathic pain to include significant changes in spinal support cells called Microglia. Now it’s been shown that “newly identified CD11c-positive microglia as a subset that increases during the remission phase of neuropathic pain”. Jeff … Continue reading

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Ehlers-Danlos / Hypermobility Syndrome is oft a Small Fiber Neuropathy Pain Syndrome and Dysautonomia/POTS

61% of Ehlers-Danlos (EH) syndromes cases have small fiber neuropathy Fibromyalgia(FM) is now, in the worser forms, considered a small fiber neuropathy and in the milder forms with evidence of skin nerve immune attack. Hence EH could be said to … Continue reading

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Celine Dion Should Not Have to be Disabled

Diffuse idiopathic skeletal hyperostosis (DISH) disability should be ameliorated, by use of IV pamidronate, Vitamin D 3 4000 u/day and  methyl f0rm B12 3000 mg/day.  HCG shots are helpful. Mood could be relieved with Transcranial magnetic stimulation and hyperbaric oxygen … Continue reading

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Plantar stretching for Plantar fasciitis

Despite some thinking there is nothing that could be done for plantar fasciitis, combination of fascia exercises (prior post) and plantar stretches combined with high dose arthritis pills (often combined with an ulcer pill) can lead to satisfactory relief.  Regular … Continue reading

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Fascial based Exercises For Plantar Fasciitis

Put foot on stairs (or a block of wood would do) and drop heel down – NOT really a stretch but strengthening and revising the plantar fascia has good effect on plantar fasciitis

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Plantar Fasciitis Statistically Shockwave Treatments Beat Botulinum but…

Botulinum injections in Plantar fasciitis had an appeal because of the lack of atrophy you can get with steroid inject.  Shockwave therapy is an option, and works in more people but pain relief looks same or better in Botulinum group?

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Plantar Fasciitis Steroid Injections – Good and Bad News

Good news is a recent meta- analysis concluded that steroid injections did not result in plantar fascia thinning. Bad news is that though it is effective, it wears off in 4-12 weeks. Rare plantar fascia ruptures can occur just like … Continue reading

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Dysfunction of Hydroxymethylglutaryl-CoA (HMG-CoA) Reductase behind some Limb Girdle Muscular Dystrophy and Statin Muscle Problems and Treatable

Exciting discovery! Hydroxymethylglutaryl-CoA (HMG-CoA) Reductase is involved in cholesterol metabolism and cholesterol pills block that enzyme. People with a less functioning version of that enzyme ended up with statin induce myopathy according to one study. Another study found it implicated … Continue reading

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B6 / Pyridoxine 100 mg for Nerve Pain

I’m a big advocate of B12 for nerve damage pain but have added B6 to my regimen as came across article using it for drug induced neuropathy. Been previously shown to help carpal tunnel symptoms. B6 is touchy as 400 … Continue reading

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Vitamin D in Dogs – are we missing the boat? – Arthritis and Itching

Dogs cannot make vitamin D – not even from sun and hence are totally dependent on diet. Osteoarthrtis in humans is only  protected in humans with HIGH vitamin D levels. Might this apply to my dog as well? Below article … Continue reading

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Emotional and Physical Pain Might Be a Memory Engram and How to Prevent It

Dr. AV Apkarian has pioneered the idea that brain changes occur following pain injury that leaves a pain memory. Mansour, A. R., M. A. Farmer, M. N. Baliki, and A. Vania Apkarian. “Chronic pain: the role of learning and brain … Continue reading

Posted in Neck, pain mechanisms, psychology | Leave a comment

Vitamin B12 in Chronic Pain

Since it was found that high dose B12 shots can almost double life expectancy of victims with ALS, the use of B12 shots has taken a new life

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