Confirmation of Nerve Growth in Tendonopathy – in Shoulder Too

I have previously written:
Does Pain “Grow” at Tendon injury sites? -and Treatment tennis elbow

Now for shoulder tendonopathy, “increases of newly grown nerve fibers and blood vessels ” inside tendons has been found

Sports Med Arthrosc. 2011 Dec;19(4):354-9.
Neoinnervation in rotator cuff tendinopathy.
Xu Y, Bonar F, Murrell GA.  abstract here

  • [various biochemical markers and staining for nerve fibers demonstrate] “that early tendinopathy is associated with increases of newly grown nerve fibers and blood vessels inside and around tendinopathic tendon”
  • So angiogenesis and nerve fiber growth can become a new target for treatment of these conditions. Certainly, in models of arthritis, it has been found to play a major role:
      Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis.
    Ashraf S. Mapp PI. Walsh DA.
    Arthritis & Rheumatism. 63(9):2700-10, 2011 Sep.
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