Category Archives: neuropathic

Algorithm For Post Hernia Pains

Concise choice selections for what to do with nerve damage level post hernia pains. I love algorithms – they are so practical.

Posted in neuropathic, Post Hernia | Leave a comment

Resistent Post Herpetic Neuralgia Treatments – IV Magnesium for Neuropathic Pains

Three IV Magnesium  1mg /k in 100 mls saline  infusions over 1 hour – one every other day or Three 1 mg/kg Ketamine in 100 mls saline infused in over 1 hour ketamine  one EOD resulted in 7/15 magnesium and … Continue reading

Posted in central & spinal, complex regional pain, Drugs, IV therapy, neuropathic, Pain Dystrophy, post herpetic neuralgia, radiculitis | 1 Comment

Is Sensitive Skin Neuropathic?

Study in Dermatology journal suggests 1/5 of subjects test positive with quiz DN4  for neuropathy

Posted in mast cell disease, neuropathic | Leave a comment

Complex Regional Pain Syndrome (CRPS) – Finding Immune Mechanims Offers New Treatments

Finding high levels of  beta2 adrenergic receptor autoantibodies in CRPS cases might explain why steroids, tumour necrosis factor (TNF)-alpha antagonist Adalimumab, IV Immmunoglobulins, and in present article Plasmapheresis can help in selected cases. In present study, these antibody titres fell … Continue reading

Posted in Botox, complex regional pain, Drugs, Injection, IV therapy, neuropathic, Pain Dystrophy, Stimulation | 1 Comment

Low Dose Neuropathic Pain Drugs Only Work in Combo – and then only a Bit

Neuropathic pain drugs by self have mediocre effects – often dropping pain by </= 2/10 points. At low dose Imipramine 75 mg/day and Pregabalin 300/day did not have significant benefit but the combo dropped VAS by One more than placebo … Continue reading

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Post Herpetic Neuralgia – Peripheral Nerve Stimulators

I have heard of peripheral nerve stimulators used in cases before but this additional one makes it more mainstream. This one captured control with high frequency

Posted in Mechanical aids, neuropathic, post herpetic neuralgia | Leave a comment

Burning Mouth Syndrome – Early? – Get treated For Herpesvirus

Case  Burning Mouth Syndrome under 6 month old was found to have high herpesvirus DNA in saliva, and improved with herpesvirus treatment (which also cleared the DNA from saliva)

Posted in ENT, neuropathic | Leave a comment

Neuropathic Pain 2015 and…

Mayo clinic has a review but lacks imagination

Posted in Botox, Drugs, Fibromyalgia, neuropathic | Leave a comment

Phantom Limb -tDCS Scalp Stimulation Reduced it 40% -Immediate and Sustained

A sustained 40% improvement was obtained from direct current 1.5 milliamp voltage – about what a 9 volt battery hooked up with a 10 k potentiometer resistor could furnish.

Posted in Mechanical aids, neuropathic, Pain Dystrophy | Leave a comment

Breathtaking Option for Treatment Resistant Fibromyalgia

A Water pill, Spironolactone 100-200 mg/day, can dramatically relieve pain in potentially 1/2 of Fibromyalgia cases and reduce morphine needs.

Posted in Drugs, Fibromyalgia, neuropathic | 2 Comments

Desimpramine For Neuropathic Pain a Myth

Use of  Tricyclic antidepressants (TCA)’s for neuropathic pain was based on an article for diabetic neuropathy where, through frequent phoning and support, authors were able to get patients up to 150 mg. No one has succeeded in getting people up … Continue reading

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Drugs for Diabetic Neuropathy

 Should we believe these results?  A study on treatment for diabetic neuropathy pretends one treatment is better than onother because on group starts with more severe pain than the other then claims each treatment can virtually eliminate pains with 7 … Continue reading

Posted in neuropathic, Uncategorized | Leave a comment

Chemotherapy Neuropathy – Prevent and Treament

Use of agents to reduce chemotherapy induced peripheral neuropathy confounded by issues of decreased anti-cancer effectiveness. L-Acetyl Carnitine during chemotherapy, and Venlafaxine or Duloxetine after are my choices.  Tricyclics, gabapentin, lyrica, and topical agents did not rate well and belie … Continue reading

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Reaching “Critical Mass” to Achieving Pain Control – Procedure Pearls

I have recently achieved (previously unattainable) control in some of my chronic pain subjects using recent innovations – but to acheive this required use of multiple modalities at once.

Posted in arm, Back Pain, Botox, complex regional pain, Drugs, Fibromyalgia, Headaches, Injection, IV therapy, Leg Pains, Manual Med, myofascial pain, Neck, neuropathic, Pain Dystrophy, piriformis, post herpetic neuralgia, radiculitis, shoulder, Uncategorized | 5 Comments

Carpal Tunnel Syndrome and Vitamin B6

For years, it was suggested that people with carpal tunnel should take B6, but it fell out of favour ( in my mind) when excessive B6 was found to be neurotoxic. Now a recent study has confirmed use of B6 … Continue reading

Posted in Drugs, hand, neuropathic | 1 Comment

Flossing Saphenous Nerve For Saphenous Neuralgia

saphenous neuralgia is not uncommon – here is how to free it up (floss it)

Posted in Leg Pains, neuropathic, Uncategorized | Leave a comment

Is Nortriptyline Any Good? – Maybe – but Maybe Only a Bit

Recently, nortriptyline has been touted as good anti-neuropathic drug but thoughts of its use have extended into use for chronic pain in general.  Well, it doesn’t work for back pain, sciatica or migraines so that might need reanalysis.

Posted in Back Pain, Drugs, neuropathic | Leave a comment

Could Statins Help Prevent or Treat Neuropathy?

After classic sciatic nerve constriction in rats, spinal/nerve elevations of Tumor Necrosis Factor (TNF),  matrix metalloproteases (MMP-2) and nerve growth factor (NGF) were some ameliorated by Atorvastatin. In a human case report, atorvastatin reduced neuropathic pain.

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Fibromyalgia – Further Elucidation of Small Fiber Neuropathy Presence.

With Both neuropathic level pains, and paresthesias common in Fibromyalgia; the idea Fibromyalgia is a small fiber neuropathy, was presented in 2010. Now an extremely thorough followup was presented again confirming this issue. They found a a “pathological process involving … Continue reading

Posted in Fibromyalgia, neuropathic | 1 Comment

Antidepressants Just Don’t Work on Descending Inhibition

Neurobiol Dis. 2013 Dec;60:39-50.Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism. Bohren Y, Tessier LH, Megat S, Petitjean H, Hugel S, Daniel D, Kremer M, Fournel  S, Hein L, Schlichter R, Freund-Mercier MJ, Yalcin I, Barrot M. … Continue reading

Posted in Drugs, neuropathic, Uncategorized | Leave a comment

Both Subcutaneous and Perineural Botulinum Treatments Advocated

Review has concluded both subcutaneous and perineural treatments are effective in neuropathic pains.

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Chemotherapy Neuropathy – Drug Combo Helps Pains

Combo Pregabalin(lyrica) and Duloxetine(Cymbalta) was able to control paclitaxel induced peripheral neuropathy.

Posted in breast cancer, neuropathic | Leave a comment

Obscure Groin Pain Could Be Lumbar Disc Even if Back Not Painful

Five  cases of groin pain that refused deliniation  and had NO back pains. They all turned out to be L4/5 or L5/S1 disc pain found on discogram/discoblock.  They all got relief with anterior intrabody fusion.

Posted in Back Pain, central & spinal, neuropathic | Leave a comment

Acromegaly Peripheral Neuropathy Responded to 5% Baclofen

Subject treated for acromegaly developed peripheral neuropathy and could not tolerate oral meds. Though pain was 9/10;  5% baclofen once daily, profoundly reduced pains in legs.

Posted in neuropathic, Topical Pain Treatments | Leave a comment

Tremor In Inflammatory Neuropathy

Non-diabetic painful numbness in hands/feet is often caused by inflammatory neuropathy. Tremor is common in these disorders and does not respond to usual treatments

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