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Category Archives: neuropathic
Pulsed radiofrequency to dumb down treated nerve is becoming a useful adjunct to treating untenable pain CRPS states. Post hip fracture leg painv pain state left patient with VAS 6-7/10 with breakthru of 9/10. Following dropped to 3/10 – after … Continue reading
0.05% Methylene Blue oral rinse therapy was cheap and effective treatment for mucositis from chemotherapy or radiotherapy. Amazing result could be big help.
A simple perivulvar way to do pudental like blocks, if repeated, can lead to astounding improvement in pain in perineal areas – either vulvodynia or pudental neuralgia. I have achieved control in one case of either but don’t know yet … Continue reading
6-8 years ago a brief neuralgic pain in the scalp that radiated to front or back of head was described. I wrote about it here: http://painmuse.org/?p=1516 Now a facially originated version has been defined and sounds very much like trigeminal … Continue reading
Both clonidine 0.1% gel and capsaicin 0.75% cream three times daily can drop pain by 40% in 12 weeks though clonidine causes less skin irritation.
In seeing new pain patients, I became painfully aware that Celiac or at least gluten sensitivity has a definite presence- so much so that I always looked for it. Now, it looks like “anybody is fair game” now that even … Continue reading
Have and elderly fellow that just persevered with severe left groin pain as was just something he should put up with. He had not been sleeping and daughter noted cognitive decline with it. Exam of hip was a bit sore … Continue reading
Though 20 week vegan diet touted as helping diabetic neuropathy, its pain levels were no different than the B12 control and the foot skin conductance was not different. Only diffence was in McGill Pain questionnaire in the sensory fields. Unfortunately, … Continue reading
For Diabetic Neuropathy – Recent study in China showed statistical significant drop of pain on Duloxetine but not clinically significant. – Have a look.
Douleur Neuropathique in 4 Questions (DN4) proved more sensitive to neuropathic pain in cancer than the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) – 87.5% for DN4 versus 68.1% for LANSS in sensitivity. However LANSS had slightly better specificity … Continue reading
The initial study of use of Amitriptyline was a study with diabetic neuropathy where patients were subject to impressive coaching (calls from nurse and pharmacist) . That way doses of 75-150 mg were obtained. They were able to show benefits. … Continue reading
Concise choice selections for what to do with nerve damage level post hernia pains. I love algorithms – they are so practical.
Three IV Magnesium 1mg /k in 100 mls saline infusions over 1 hour – one every other day or Three 1 mg/kg Ketamine in 100 mls saline infused in over 1 hour ketamine one EOD resulted in 7/15 magnesium and … Continue reading
Study in Dermatology journal suggests 1/5 of subjects test positive with quiz DN4 for neuropathy
Finding high levels of beta2 adrenergic receptor autoantibodies in CRPS cases might explain why steroids, tumour necrosis factor (TNF)-alpha antagonist Adalimumab, IV Immmunoglobulins, and in present article Plasmapheresis can help in selected cases. In present study, these antibody titres fell … Continue reading
Neuropathic pain drugs by self have mediocre effects – often dropping pain by </= 2/10 points. At low dose Imipramine 75 mg/day and Pregabalin 300/day did not have significant benefit but the combo dropped VAS by One more than placebo … Continue reading
I have heard of peripheral nerve stimulators used in cases before but this additional one makes it more mainstream. This one captured control with high frequency
Case Burning Mouth Syndrome under 6 month old was found to have high herpesvirus DNA in saliva, and improved with herpesvirus treatment (which also cleared the DNA from saliva)
Mayo clinic has a review but lacks imagination
A sustained 40% improvement was obtained from direct current 1.5 milliamp voltage – about what a 9 volt battery hooked up with a 10 k potentiometer resistor could furnish.
A Water pill, Spironolactone 100-200 mg/day, can dramatically relieve pain in potentially 1/2 of Fibromyalgia cases and reduce morphine needs.
Use of Tricyclic antidepressants (TCA)’s for neuropathic pain was based on an article for diabetic neuropathy where, through frequent phoning and support, authors were able to get patients up to 150 mg. No one has succeeded in getting people up … Continue reading
Should we believe these results? A study on treatment for diabetic neuropathy pretends one treatment is better than onother because on group starts with more severe pain than the other then claims each treatment can virtually eliminate pains with 7 … Continue reading
Use of agents to reduce chemotherapy induced peripheral neuropathy confounded by issues of decreased anti-cancer effectiveness. L-Acetyl Carnitine during chemotherapy, and Venlafaxine or Duloxetine after are my choices. Tricyclics, gabapentin, lyrica, and topical agents did not rate well and belie … Continue reading
I have recently achieved (previously unattainable) control in some of my chronic pain subjects using recent innovations – but to acheive this required use of multiple modalities at once.