Fibromyalgia Common in Thyroid Disease

In Hashimoto’s thyroiditis, quoted FM rate is 30-40% ; present study found 62%.  Thyroid antibodies, abdominal girth, and duration disease among other things, contribute to FM possibility.

Clin Rheumatol. 2017 Jul;36(7):1617-1621. doi: 10.1007/s10067-017-3556-2.
Fibromyalgia in patients with thyroid autoimmunity: prevalence and relationship with disease activity.
Haliloglu S et al
https://www.ncbi.nlm.nih.gov/pubmed/28176037

  • 79 cases Hashimoto’s thyroiditis (HT)
  • Hasimoto’s also called chronic lymphocytic thyroiditis
  • Other thyroid disease is Grave’s disease
  • about 10% women and 1% men have Hashimoto’s
  • “diagnosis of HT was made based on the presence of positive antithyroid peroxidase antibody (TPOAb) and antithyroglobulin antibody (TgAb) titres and the typical ultrasonography findings”
  • Prevalence Fibromyalgia was 62%

Correlated with Fibromylagia:

More likely in:

  • Older age
  • longer duration of thyroiditis
  • thyroid lab abnormalities – TSH and thyroid antibody levels
  • Obesity – higher BMI and wider abdominal girth
  • lower height
  • lower education level ( maybe sign of illness) but not income level
  • married status

Comment – This fits with my concept that Fibromyalgia is an autoimmune disease. Small fiber neuropathy seen in 40+% is a feature of that. Recently, 10+% were found to have MRI evidence of frank active spondyloarthitis another autoimmune type.

\What is interesting is that patients on thyroid replacement often end up with bacterial overgrowth:
Bacterial Overgrowth and Irritable Bowel Syndrome (IBS) – What is the Hypothyroid/Levothyroxine Connection?
http://painmuse.org/?p=5256

I check for thyroid antibodies in FM subjects and now it seems even more important.

This entry was posted in Fibromyalgia. Bookmark the permalink.

Leave a Reply

Your email address will not be published.