Use of Bio Skin Q Brace in Patellofemoral Arthritis

Bio Skin® Q Brace™ reduced pain in knee patellofemoral OA and reduced bone marrow edema seen





A randomised trial of a brace for patellofemoral  osteoarthritis targeting knee pain and bone marrow lesions
Michael J Callaghan et al
Ann Rheum Dis 2015 in press. doi:10.1136/annrheumdis-2014-206376

  • randomized control trial
  • 6 wks brace
  • mean of 7.4 hrs/day

Followed evidence of bone marrow edema:
















  • No brace had a VAS of 6.3; brace one of 5 (mediocre difference)
  • bone marrow edema less in brace one
  • didn’t keep good track of NSAID use

Comment – treatment of bone marrow edema unsatisfactory with both Zoledronic acid (IV once bone building ), Ibandronate bone building and prostaglandin I2 being tried:

Laslett, Laura Louise, et al.
“Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial.”
Annals of the rheumatic diseases (2012): annrheumdis-2011.

Bartl, C., Imhoff, A., & Bartl, R. (2012).
Treatment of bone marrow edema syndrome with intravenous ibandronate.
Archives of orthopaedic and trauma surgery, 132(12), 1781-1788.


Jäger, Marcus, et al.
“Rationale for prostaglandin I2 in bone marrow oedema–from theory to application.” Arthritis research & therapy 10.5 (2008): R120.

Brace appears to help a bit.





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