Low Vitamin D associated with Osteoarthritis

This is not necessarily new – Framingham study found that low vitamin D was associated with with “an increased risk for progression of osteoarthritis of the knee” back in 1996. This seems to have been forgotten.  Now a new study found “Participants with adequate 25(OH)D levels reported significantly less knee osteoarthritis pain compared to participants with deficient or insufficient levels, regardless of obesity status”.

Clin J Pain. 2015 Jan 7. [Epub ahead of print]
A Cross-Sectional Examination of Vitamin D, Obesity, and Measures of Pain and
Function in Middle-Aged and Older Adults with Knee Osteoarthritis.
Glover TL

  • Obese subjects were found to have lower Vitamin D
  • However, when obesity was adjusted for, low vitamin D patients had more OA knee pains

Comment :

For those interested, the framingham study is here:

Relation of Dietary Intake and Serum Levels of Vitamin D to Progression of Osteoarthritis of the Knee among Participants in the Framingham Study
Timothy E. McAlindon et al
Ann Intern Med. 1996;125(5):353-359.

In study in Calgary, Alberta, Canada found that virtually all subjects were low some part of the year if they were not on supplements. I check blood levels and they are always low. I think it as sleeping giant leading eventually to pain, weakness, osteoporosis, and falls in our elderly population.


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One Response to Low Vitamin D associated with Osteoarthritis

  1. Pingback: One Reason Osteoarthritis Bad in Canadian Prairies – Persistent Low Vitamin D Levels | Pain Medical Musing

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