Evista / Raloxifen For Fibromyalgia Pain and Fatigue – Why Has No One Confirmed It?

Raloxifen is a estrogen look alike used for osteoporosis. Is is similar to tamoxifen so helps to prevent breast cancer. Like birth control pills, has a slight stroke risk.

I have a relative who had been on raloxifen for Osteoporosis. It, in combination with other meds has been relatively effective. Her sister has had a fracture, worse hearing loss, and was at one point diagnosed with Fibromyalgia.

It turns out, and article with no referencing to, described raloxifen as a treatment for fibromylagia pain and fatigue in a double blind trial. The study was never repeated and came on it by accident. Pain was cut to more than half in 4 months and fatigue helped as well.

Sadreddini, Shahram, et al.
Efficacy of Raloxifen in treatment of fibromyalgia in menopausal women.
European journal of internal medicine 19.5 (2008): 350-355.

  • 49 Raloxifen 60 mg od and 47 cases placebo 16 weeks

deafness is related to osteoporosis some:

Kim, Ji Yoon, et al.
Hearing loss in postmenopausal women with low bone mineral density.
Auris Nasus Larynx 43.2 (2016): 155-160.


Comment – Why is there little notice or replication of this study ?- I will have to add this to my list of helpful agents…

addendum-there was a prior article showing benefit it osteoarthritis:

New Painkiller for Back & Knee Pains – Raloxifene (Evista) – a drug for Osteoporosis


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