Gabapentin Fails Again – Does Not Work in Chronic Pelvic Pains

While gabapentin might work in post herpetic neuralgia and diabetic neuropathy, it does not work well in spinal pains/sciaticas and so forth. Now it has been shown not to work in chronic pelvic pains as well.

Horne AW, Vincent K, Hewitt CA, Middleton LJ, Koscielniak M, Szubert W, Doust AM, Daniels JP; GaPP2 collaborative.
Gabapentin for chronic pelvic pain in women (GaPP2): a multicentre, randomised, double-blind, placebo-controlled trial.
Lancet. 2020 Sep 26;396(10255):909-917.
doi: 10.1016/S0140-6736(20)31693-7. PMID: 32979978; PMCID: PMC7527829.


“This study was adequately powered, but treatment with gabapentin did not result in significantly lower pain scores in women with chronic pelvic pain, and was associated with higher rates of side-effects than placebo”

comment – not a big fan of gabapentin

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