Putting together info on using newer agents. Note: DPP4 and SGLT2 combo not allowed by EDS. Lectures from Dr. Sue Petersen 2017
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Must watch GFR
Exemption Status re new drugs expects sulfonylurea to be used with metformin first.
linagliptin, tablet, 5mg (Trajenta-BOE) (possible OEA)
For treatment of patients with Type 2 diabetes who have had previous prescriptions for metformin and a sulfonylurea.
Please Note: This product should be used in patients with diabetes who are not
adequately controlled on or are intolerant to metformin and a sulfonylurea, and for whom insulin is not an option.
5 mg od
sitagliptin phosphate, tablet, 100mg (Januvia-MRK) (possible OEA)
For treatment of patients with Type 2 diabetes who have had previous prescriptions for metformin and a sulfonylurea.
Please Note: These products should be used in patients with diabetes who are not adequately controlled on or are intolerant to metformin and a sulfonylurea, and for whom insulin is not an option.
100 mg od; moderate gfr (30-50)- 50; severe – 25 mg od
canagliflozin, tablet, 100mg, 300mg (Invokana-JAN) (possible OEA)
For treatment of patients with Type 2 diabetes who have concurrent prescriptions for metformin and a sulfonylurea.
This product should not be used in combination with dipeptidyl peptidase-4 inhibitors.
Please note: This product should be used in patients with diabetes who are not adequately controlled on or are intolerant to metformin and/or a sulfonylurea, and for whom insulin is not an option
100 mg od start – work up to 300 mg od
empagliflozin, tablet, 10mg, 25mg (Jardiance-BOE) (possible OEA)
For treatment of patients with Type 2 diabetes who have concurrent prescriptions for metformin and a sulfonylurea.
This product should not be used in combination with dipeptidyl peptidase-4 inhibitors.
Please note: This product should be used in patients with diabetes who are not adequately controlled on or are intolerant to metformin and/or a sulfonylurea, and for whom insulin is not an option.
start with 10 mg od; work up to 25 mg od
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Victoza – no coverage.
start o.6 mg/day to max 1.8 mg/day
nausea; wt loss
Byetta – no coverage
start 5 mcg bid within 1 hour after eating up to 10 bid
If sick, Diabetic should stop: SAD MANS
S -Sulfonylureal
A – ACE
D – duiretic
M – Metformin
A – ARB
N – NSAID
S – SGLT2 nike air max womens nike air max womens