Dry eyes was significantly improved by repeated injections of platelet rich plasma around lacrimal galnd
Cornea. 2014 Jan;33(1):18-21.
Restoration of human lacrimal function following platelet-rich plasma injection.
- “Ten milliliters of whole blood was collected by venopuncture in sterile tubes containing sodium citrate 0.5 mL (Beckton Dickenson). The blood was centrifuged at 160g for 10 minutes. The plasma was isolated (~5 mL per patient) and centrifuged again at 160g for 15 minutes. The inferior 1 mL was isolated, and 0.1 cm3 of CaCl was added to activate platelets. “
- “This fraction was injected in the external one-third of the orbital rim and 4 mm in depth to the superior area. The rference was the area of the lacrimal fossa in the frontal one. This anatomic area corresponds to the localization of
the lacrimal gland.”
- Platelet rich-activated plasma (1 mL) was injected adjacent to the lacrimal gland on day 0 and at 4, 8, and 12 weeks
“RESULTS: All cases showed a significant improvement in lacrimal volume (from 3.3 +/- 0.8 mm to 11.1 ± 2.3 mm). In all the patients, an increase in tear break-up time values and a decrease in ocular staining (basal 8.0 ± 0.61-2.8 ± 0.5) with subjective improvement occurred. None of the patients presented any adverse effect, and none reported pain or discomfort. Additionally, no complications were observed.”