Vitamin C Strikes Again – ?Prevents Post Surgical Wrist Complex Regional Pain and Obviously Post Foot/Ankle Surgery CRPS

Severe pain after trivial injuries or surgery has been a fearful hazard. Now Vitamin C has been shown to perhaps prevent pains after wrist surgery

Open Orthop J. 2010 Feb 17;4:71-5.
No Higher Risk of CRPS After External Fixation of Distal Radial Fractures – Subgroup Analysis Under Randomised Vitamin C Prophylaxis.
Zollinger PE, Kreis RW, van der Meulen HG, van der Elst M, Breederveld RS, Tuinebreijer WE.
“In the operated group of patients who received vitamin C no CRPS (0/37) was seen in comparison with one case of CRPS (Kapandji technique) in the operated group who received placebo (1/11 = 9%, p=.23)”

OK – not exactly statistically great but still zero cases is zero cases.

Previously, Vitamin C has been shown to help prevent pain:

  • After wrist fractures
  • After shingles:

Helping Prevent and Treat Post Shingles Pain / Post Herpetic Neuralgia – Can It Be as Simple as Vitamin C to Help

Anyone having surgery or having significant trauma injury should be taking 500 mg twice daily of vitamin C.

Addendum:

Recent article discusses this further:

Korean J Pain. 2012 Jul;25(3):200-1.
Vitamin C and its emerging role in pain management: beneficial effects in pain conditions besides post herpetic neuralgia.
Kapoor S.         free article here

They mention another surgical article:
Besse JL, Gadeyne S, Galand-Desmé S, Lerat JL, Moyen B.
Effect of vitamin C on prevention of complex regional pain syndrome type I in foot and ankle surgery.
Foot Ankle Surg 2009; 15: 179-82. abstract here

  • After foot and ankle surgery
  • tourniquet  and cast immobilisation used – both can cause vascular damage that is involved in CRPS
  • 1 gm in AM vitamin C/day morning after surgery and for 45 days
  • 185 in Control group; 235 in Vitamin C (Big study)
  • 9.6% Complex regional pain in control group and 1.7% in Vitamin C group (p< 0.00001)

 

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