Capsaicin 8% Patch in Peripheral Neuropathy Not Diabetic but at a Cost…

Capsaicin 8% patch was compared to pregabalin (lyrica) for effects on non-diabetic peripheral neuropathy.  A treatment with Capsaicin can cut skin sensitivity (dynamic mechanical allodynia) in half and render 29% free of sensitivity. Was embarrassed to publish this once I found out how much the patch costs ($800/patch in 2012)

Eur J Pain. 2018 Apr;22(4):700-706.
doi: 10.1002/ejp.1155
Superiority of capsaicin 8% patch versus oral pregabalin on dynamic mechanical allodynia in patients with peripheral neuropathic pain.
Cruccu G et al

  • 253 case of nerve injury or non-diabetic peripheral neuropathy with pain >/= 4/10
  • half group was put on pregabalin 150 – 600 mg/day
  • area involved determined by lightly brushing edges – marked
  • can use up to 4 patches to area marked

instructions are here;

  • medical office treatment
  • apply a topical numbing gel – lidocaine was recommended but not convinced works that well – maybe occlude  and have on 30-60 minutes
  • take a painkiller -plus I would use ketamine 10 mg M deltoid once or twice every 15 minutes as I am comfortable  used to using it
  • wear gloves
  • apply to affected areas and cover
  • have on 30-60 minutes
  • removed by slowly rolling edge
  • apply cleansing gel and wipe off
  • avoid touching eyes
  • skin will be sensitive a few days
  • do every 3 months

results at week 8:
Complete resolution of pain in 24.1% of patches and 12.3% of pregabalin at 8 weeks side effects were pain and eythema at time of treatment but were manageable.

Comment – would be a great addition to treatment except the cost

“One capsaicin 8% patch costs approximately $800 (US) in 2012

as per:
Groninger H, Schisler RE. Topical Capsaicin for Neuropathic Pain #255. Journal of Palliative Medicine. 2012;15(8):946-947. doi:10.1089/jpm.2012.9571.

If you need cheap, start with amitriptyline hs and work up. nike air max womens nike air max womens

This entry was posted in neuropathic, Topical Pain Treatments. Bookmark the permalink.

One Response to Capsaicin 8% Patch in Peripheral Neuropathy Not Diabetic but at a Cost…

  1. Susan Lauer says:

    Capsaicin cream is sold here in the US at Amazon for $12.00 a tube of 1 1/2 ounces of 10%. It is cheaper even at Walmart. I take it and mix it in a jar with 4% lidocaine cream-4.7 oz-for $9.98 at Amazon.
    I normally mix 3/4 Lidocaine with 1/4 Capsaicin cream. For large areas, I paint it on witih a 2″ paintbrush-the very flat type so the cream isn’t wasted. You can also use the back of a tablespoon.
    For a small area that is severely painful, I put it on straight.
    I have gotten completely off of painkillers except 2 Excedrin in the AM.

Leave a Reply

Your email address will not be published.