Peripheral Neuropathy Pain Unresponsive to Creams – Try 5% Doxepin

Child cancer case where chemotherapy induced peripheral neuropathy pain was not helped by usual topicals was helped by 5% doxepin cream

BMJ Case Rep. 2017 May 22;2017. pii: bcr-2017-219900. doi:
Severe medication-induced peripheral neuropathy treated with topical doxepin
cream in a paediatric patient with leukaemia.
Dworsky ZD et al

  • childhood leukemia
  • failure usual topicals
  • dramatic response to 5% topical doxepin

Comment – 5% doxepin cream is marketed by Valeant in Canada as an anti-itch cream. Doxepin capsules are cheap and if you took¬†¬† contents of 20 capsules in 100 mls of some penetrating gel or cream then you could potentially make it yourself…

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