Advanced Gallbladder Testing Can Miss Disease

Two approaches to gallbladder advanced testing – use of fatty meal (FM) as a substitute for cholecystokinin (CCK) in pain reproduction during hepato-imino-diacetic acid (HIDA) scan in functional gallbladder disorder. – will miss 1/2 of cases

Hepatobiliary Pancreat Dis Int. 2017 Apr;16(2):197-201.
HIDA scan for functional gallbladder disorder: ensure that you know how the scan was done.
Goussous N et al
https://www.ncbi.nlm.nih.gov/pubmed/28381385

  • HIDA scan – 70 received CCK and 83 fatty meal
  • Pain reproduction in 30% fatty meal and 61% CCK   p<0.01
  • no difference in demographic factors or pain – ie you can’t tell who will fail

Comment – there is always the urge to cut costs and a fatty meal is not an adequate test so do what the article said “ensure you know how the scan was done”

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