Carpal Tunnel Syndrome and Vitamin B6

For years, it was suggested that people with carpal tunnel should take B6, but it fell out of favour ( in my mind) when excessive B6 was found to be neurotoxic. Now a recent study has confirmed use of B6 in carpal tunnel syndrome.

Adv Pharm Bull. 2013;3(2):283-288.
Effect of Vitamin B6 on Clinical Symptoms and Electrodiagnostic Results of Patients with Carpal Tunnel Syndrome.
Talebi M, Andalib S, Bakhti S, Ayromlou H, Aghili A, Talebi A.
http://www.ncbi.nlm.nih.gov/pubmed/24312849

• B6 120 mg/day for 3 months plus wrist splinting  vs just splinting
• “Results: Nocturnal awakening frequency due to pain, daily pain, daily pain frequency, daily pain persistence, hand numbness, hand weakness, hand tingling, severity of nocturnal numbness and tingling, nocturnal awakening frequency owing to hand numbness and tingling, and clumsiness in handling objects improved significantly in the vitamin B6-treated patients; even so, only problem with opening a jam bottle and handling phone significantly reduced in the control group. The median nerve sensory latency mean decreased following the treatment; and the median nerve sensory amplitude mean and sensory conduction velocity mean increased”
• Our university does not get that  journal so will have to leave it at that.