Monthly Archives: May 2008

Can’t Tolerate Arthritis Pills? – Try SAMe But Give It a Month.

Posted on May 12, 2008 by admin

Most NSAID’s (arthrtis pills) have a GI bleed (stomach bleed) rate of 10%. Diclofenac is 7%. Celebrex is 5% but only if they are not taking ASA. I have cases that cannot tolerate any NSAID’s or due to major GI … Continue reading →

Posted in arthritis, Drugs | 1 Comment

Migraine treatment options

Posted on May 11, 2008 by admin

Some years ago, I came across a graph, that explained some migraine treatments options. I found it handy to show patients but have upgraded it. The original graph was this: Therapeutic gain of migraine prophylaxis compared to placebo. Graph shows … Continue reading →

Posted in Headaches | 2 Comments

Microglia Key to Neuropathic Pain

Posted on May 11, 2008 by admin

While much is written about gimped NMDA receptors in chronic pain, the innocuous support tissues in the spinal cord, the “glial cells”, turn out to be a big player. An inhibitor of these cells, clopidogrel – known as Plavix – … Continue reading →

Posted in neuropathic, Pathophysiology | 2 Comments

Dyspepsia (Indigestion) Under 45 – Eradicate Helicobacter Pylori

Posted on May 11, 2008 by admin

Controversy abounds over whether People with dyspepsia should have H. pylori colonization treated. Recent article concludes “The main therapeutic strategy for managing dyspepsia in patients under the age of 45 years is ‘test and treat’. H. pylori eradication is recommended … Continue reading →

Posted in Abdominal pain | Leave a comment

Mast Cells and Histamine Receptors Cause Pain in Interstital Cystitis (IC) and We Must Deal Better With Peripheral Pain Generators

Posted on May 9, 2008 by admin

Startling findings from gene deletion mice experiments implicate mast cells and histamine receptors in IC. It is also implicated that other peripheral sensitizations might follow that process.

Posted in Interstial Cystitis/Gynecologic | 1 Comment